Correlation Engine 2.0
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QuickView for type I DNA topoisomerase;jsessionid=3884DBE72E648BCB5CD160CA4DE8151C;jsessionid=5F5FDCD8678D3AF43B9A151241B37279 (gene)


Gene Symbol:
Top1 D. melanogaster D. melanogaster
Full name:
Topoisomerase 1
Synonyms:
CG6146, DmelCG6146, Dmel_CG6146, dTopoI, l(1)G0134, l(1)G0201, l(1)G0229, l(1)G0278, l(1)top1, Top1, TOP1, TOP1, TopI, Topo I, TopoI, topoI
Genomic Location:
Chr X: 15213525-15222062
Orthologs:
Homo sapiens Mus musculus Rattus norvegicus C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
AACTTT_UNKNOWN ATF_01 NMYC_01 IK1_01 CEBPB_02 MYCMAX_01 MAX_01 MYCMAX_02 CEBP_01 NFKB_Q6


Transcripts Names
NM_078606
NM_001014742
NM_167435
Protein Names
Q494M1
Q8IR39
P30189
Q9VXW6



GO Molecular Function

isomerase activity | nucleic acid binding | catalytic activity | DNA binding | organic cyclic compound binding | DNA topoisomerase type I activity | heterocyclic compound binding | DNA topoisomerase activity

GO Biological Process

developmental process involved in reproduction | larval development | cell differentiation | cellular process | chromatin organization | regulation of embryonic development | multicellular organismal reproductive process | gamete generation | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | female gamete generation | chromosome segregation | germ cell development | reproduction | cellular nitrogen compound metabolic process | instar larval or pupal development | cellular biosynthetic process | nitrogen compound metabolic process | reproductive process | multicellular organism development | chromosome condensation | oogenesis | cell proliferation | biosynthetic process | instar larval development | post-embryonic development | DNA topological change | chromatin remodeling | multicellular organism reproduction | DNA metabolic process | anatomical structure development | metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | DNA packaging | cell development | cellular macromolecule biosynthetic process | regulation of developmental process | developmental process | organelle organization | DNA conformation change | heterocycle metabolic process | chromosome organization | cellular metabolic process | DNA replication | sexual reproduction | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

nuclear euchromatin | chromosome | intracellular membrane-bounded organelle | nuclear replication fork | polytene chromosome | cell | replication fork protection complex | nuclear lumen | replication fork | nucleolus | cytoplasm | intracellular organelle | euchromatin | protein-containing complex | polytene chromosome puff | chromatin | nuclear chromosome | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | nuclear chromatin | cytosol | intracellular